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Umbrella and basket trials in oncology: ethical challenges

BACKGROUND: Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referred to scientific validity, risk-benefit balance and informed consent. Our aim is...

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Bibliographic Details
Published in:BMC Med Ethics
Main Authors: Strzebonska, Karolina, Waligora, Marcin
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708208/
https://ncbi.nlm.nih.gov/pubmed/31443704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12910-019-0395-5
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