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Dendrimer conjugation enables multiphoton chemical neurophysiology studies with an extended π-electron caging chromophore.

We have developed a caged neurotransmitter using an extended π-electron chromophore for efficient multiphoton uncaging on living neurons. Widely studied in a chemical context, such chromophores are inherently bioincompatible due to their highly lipophilic character. Attachment of two polycarboxylate...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Richers, Matthew T., Passlick, Stefan, Agarwal, Hitesh, Ellis-Davies, Graham C.R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707848/
https://ncbi.nlm.nih.gov/pubmed/31216109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906067
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