Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

Multiple sclerosis (MS) is characterized by demyelinated and inflammatory lesions in the brain and spinal cord that are highly variable in terms of cellular content. Here, we used imaging mass cytometry (IMC) to enable the simultaneous imaging of 15+ proteins within staged MS lesions. To test the po...

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Sparad:
Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Ramaglia, Valeria, Sheikh-Mohamed, Salma, Legg, Karen, Park, Calvin, Rojas, Olga L, Zandee, Stephanie, Fu, Fred, Ornatsky, Olga, Swanson, Eric C, Pitt, David, Prat, Alexandre, McKee, Trevor D, Gommerman, Jennifer L
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2019
Ämnen:
Immunology and Inflammation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707785/
https://ncbi.nlm.nih.gov/pubmed/31368890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48051
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