Oncogenic Pathways and Loss of the Rab11 GTPase Synergize To Alter Metabolism in Drosophila

Colorectal cancer is a complex disease driven by well-established mutations such as APC and other yet to be identified pathways. The GTPase Rab11 regulates endosomal protein trafficking, and previously we showed that loss of Rab11 caused intestinal inflammation and hyperplasia in mice and flies. To...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Nie, Yingchao, Yu, Shiyan, Li, Qi, Nirala, Niraj K., Amcheslavsky, Alla, Edwards, Yvonne J. K., Shum, Patrick W., Jiang, Zhong, Wang, Wei, Zhang, Biliang, Gao, Nan, Ip, Y. Tony
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707446/
https://ncbi.nlm.nih.gov/pubmed/31213502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302137
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