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The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients

Anti-PD-1-based immunotherapy has had a major impact on cancer treatment but has only benefited a subset of patients. Among the variables that could contribute to interpatient heterogeneity is differential composition of the patients’ microbiome, which has been shown to affect antitumor immunity and...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: Matson, Vyara, Fessler, Jessica, Bao, Riyue, Chongsuwat, Tara, Zha, Yuanyuan, Alegre, Maria-Luisa, Luke, Jason J., Gajewski, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707353/
https://ncbi.nlm.nih.gov/pubmed/29302014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao3290
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