Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets

Although the incidence of severe fever with thrombocytopenia syndrome virus (SFTSV) infection has increased from its discovery with a mortality rate of 10–20%, no effective vaccines are currently available. Here we describe the development of a SFTSV DNA vaccine, its immunogenicity, and its protecti...

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Udgivet i:Nat Commun
Main Authors: Kwak, Jeong-Eun, Kim, Young-Il, Park, Su-Jin, Yu, Min-Ah, Kwon, Hyeok-Il, Eo, Sukyeong, Kim, Tae-Shin, Seok, Joon, Choi, Won-Suk, Jeong, Ju Hwan, Lee, Hyojin, Cho, Youngran, Kwon, Jin Ah, Jeong, Moonsup, Maslow, Joel N., Kim, Yong-Eun, Jeon, Haili, Kim, Kee K., Shin, Eui-Cheol, Song, Min-Suk, Jung, Jae U., Choi, Young Ki, Park, Su-Hyung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707330/
https://ncbi.nlm.nih.gov/pubmed/31444366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11815-4
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