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Complete Surgical Resection Following Neoadjuvant Dabrafenib Plus Trametinib in BRAF(V600E)-Mutated Anaplastic Thyroid Carcinoma

Background: When achieved, complete surgical resection improves outcomes in anaplastic thyroid carcinoma (ATC). However, most ATC patients present with advanced inoperable disease, often with impending airway obstruction, increased hemorrhage risk, and significant dysphagia. Novel treatment strategi...

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Bibliographic Details
Published in:Thyroid
Main Authors: Wang, Jennifer R., Zafereo, Mark E., Dadu, Ramona, Ferrarotto, Renata, Busaidy, Naifa L., Lu, Charles, Ahmed, Salmaan, Gule-Monroe, Maria K., Williams, Michelle D., Sturgis, Erich M., Goepfert, Ryan P., Gross, Neil D., Lai, Stephen Y., Gunn, Gary Brandon, Phan, Jack, Rosenthal, David I., Fuller, Clifton David, Morrison, William H., Iyer, Priyanka, Cabanillas, Maria E.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc., publishers 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707029/
https://ncbi.nlm.nih.gov/pubmed/31319771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0133
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