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Diastereoselective Synthesis of Potent Antimalarial Cis-β-lactam Agents
Fifteen novel β-lactams bearing N-ethyl tert-butyl carbamate group 5a-o and fifteen N-(2- aminoethyl) β-lactams 6a-o were synthesized by [2+2] ketene-imine cycloaddition reaction (Staudinger). The cycloaddition reaction was found to be totally diastereoselective leading exclusively to theformation o...
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| Veröffentlicht in: | Iran J Pharm Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Shaheed Beheshti University of Medical Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6706723/ https://ncbi.nlm.nih.gov/pubmed/31531044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2017.2024 |
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