Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells

Neuronal subtypes show diverse injury responses, but the molecular underpinnings remain elusive. Using transgenic mice that allow reliable visualization of axonal fate, we demonstrate that intrinsically photosensitive-retinal ganglion cells (ipRGCs) are both resilient to cell death and highly regene...

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Veröffentlicht in:Neuron
Hauptverfasser: Bray, Eric R., Yungher, Benjamin J., Levay, Konstantin, Ribeiro, Marcio, Dvoryanchikov, Gennady, Ayupe, Ana C., Thakor, Kinjal, Marks, Victoria, Randolph, Michael, Danzi, Matt C., Schmidt, Tiffany M., Chaudhari, Nirupa, Lemmon, Vance P., Hattar, Samer, Park, Kevin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706310/
https://ncbi.nlm.nih.gov/pubmed/31255486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.05.044
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