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A mechanosensitive GPCR that detects the bloody force

Mechanoreceptors mediate a wide variety of physiological processes, such as hearing, touch, proprioception, and blood flow regulation. It is generally believed that mechanoreceptors are force-gated ion channels. Now, Xu et al uncover a GPCR that is activated by shear force in endothelial cells of bl...

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Publicat a:Cell
Autors principals: Iliff, Adam J., Xu, X.Z. Shawn
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706248/
https://ncbi.nlm.nih.gov/pubmed/29677505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.04.001
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