Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target

INTRODUCTION: Plasmodium falciparum synthesizes phosphatidylcholine for the membrane development through serine decarboxylase–phosphoethanolamine methyltransferase pathway for growth in human host. Phosphoethanolamine-methyltransferase (PfPMT) is a crucial enzyme for the synthesis of phosphocholine...

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Udgivet i:PLoS One
Main Authors: Singh, Jagbir, Vijay, Sonam, Mansuri, Rani, Rawal, Ritu, Kadian, Kavita, Sahoo, Ganesh Chandra, Kumar, Mahesh, Sharma, Arun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705855/
https://ncbi.nlm.nih.gov/pubmed/31437171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221032
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