APOE-Sensitive Cholinergic Sprouting Compensates for Hippocampal Dysfunctions Due to Reduced Entorhinal Input

Brain mechanisms compensating for cerebral lesions may mitigate the progression of chronic neurodegenerative disorders such as Alzheimer's disease (AD). Mild cognitive impairment (MCI), which often precedes AD, is characterized by neuronal loss in the entorhinal cortex (EC). This loss leads to...

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Publicado no:J Neurosci
Main Authors: Bott, Jean-Bastien, Héraud, Céline, Cosquer, Brigitte, Herbeaux, Karine, Aubert, Julien, Sartori, Maxime, Goutagny, Romain, Mathis, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705585/
https://ncbi.nlm.nih.gov/pubmed/27707979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1174-16.2016
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