Cross-Recognition of a Myelin Peptide by CD8(+) T Cells in the CNS Is Not Sufficient to Promote Neuronal Damage

Multiple sclerosis (MS) is an inflammatory disease of the CNS thought to be driven by CNS-specific T lymphocytes. Although CD8(+) T cells are frequently found in multiple sclerosis lesions, their distinct role remains controversial because direct signs of cytotoxicity have not been confirmed in vivo...

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Pubblicato in:J Neurosci
Autori principali: Reuter, Eva, Gollan, René, Grohmann, Nadia, Paterka, Magdalena, Salmon, Hélène, Birkenstock, Jérôme, Richers, Sebastian, Leuenberger, Tina, Brandt, Alexander U., Kuhlmann, Tanja, Zipp, Frauke, Siffrin, Volker
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705380/
https://ncbi.nlm.nih.gov/pubmed/25810515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3380-14.2015
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