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Ministrokes in Channelrhodopsin-2 Transgenic Mice Reveal Widespread Deficits in Motor Output Despite Maintenance of Cortical Neuronal Excitability

We evaluated the effects of ministrokes targeted to individual pial arterioles on motor function in Thy-1 line 18 channelrhodopsin-2 (ChR2) transgenic mice within the first hours after ischemia. Using optogenetics, we directly assessed both the excitability and motor output of cortical neurons in a...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Anenberg, Eitan, Arstikaitis, Pamela, Niitsu, Yoichi, Harrison, Thomas C., Boyd, Jamie D., Hilton, Brett J., Tetzlaff, Wolfram, Murphy, Timothy H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705317/
https://ncbi.nlm.nih.gov/pubmed/24453302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1442-13.2014
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