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Spinal Glutamatergic Neurons Defined by EphA4 Signaling Are Essential Components of Normal Locomotor Circuits

EphA4 signaling is essential for the spatiotemporal organization of neuronal circuit formation. In mice, deletion of this signaling pathway causes aberrant midline crossing of axons from both brain and spinal neurons and the complete knock-outs (KOs) exhibit a pronounced change in motor behavior, wh...

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Publicat a:J Neurosci
Autors principals: Borgius, Lotta, Nishimaru, Hiroshi, Caldeira, Vanessa, Kunugise, Yuka, Löw, Peter, Reig, Ramon, Itohara, Shigeyoshi, Iwasato, Takuji, Kiehn, Ole
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705281/
https://ncbi.nlm.nih.gov/pubmed/24623763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4992-13.2014
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