Bioconjugation with Aminoalkylhydrazine for Efficient Mass Spectrometry-Based Detection of Small Carbonyl Compounds

[Image: see text] Bioconjugation through oxime or hydrazone formation is a versatile strategy for covalent labeling of biomolecules in vitro and in vivo. In this work, a mass spectrometry-based method was developed for the bioconjugation of small carbonyl compounds (CCs) with an aminoalkylhydrazine...

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Vydáno v:ACS Omega
Hlavní autoři: Thangaraj, Senthil K., Voutilainen, Sanni, Andberg, Martina, Koivula, Anu, Jänis, Janne, Rouvinen, Juha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705233/
https://ncbi.nlm.nih.gov/pubmed/31460473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01691
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