Forebrain Deletion of the Vesicular Acetylcholine Transporter Results in Deficits in Executive Function, Metabolic, and RNA Splicing Abnormalities in the Prefrontal Cortex

One of the key brain regions in cognitive processing and executive function is the prefrontal cortex (PFC), which receives cholinergic input from basal forebrain cholinergic neurons. We evaluated the contribution of synaptically released acetylcholine (ACh) to executive function by genetically targe...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kolisnyk, Benjamin, Al-Onaizi, Mohammed A., Hirata, Pedro H. F., Guzman, Monica S., Nikolova, Simona, Barbash, Shahar, Soreq, Hermona, Bartha, Robert, Prado, Marco A. M., Prado, Vania F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705170/
https://ncbi.nlm.nih.gov/pubmed/24027290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1933-13.2013
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