Extinction of Aversive Memories Associated with Morphine Withdrawal Requires ERK-Mediated Epigenetic Regulation of Brain-Derived Neurotrophic Factor Transcription in the Rat Ventromedial Prefrontal Cortex

Recent evidence suggests that histone deacetylase (HDAC) inhibitors facilitate extinction of rewarding memory of drug taking. However, little is known about the role of chromatin modification in the extinction of aversive memory of drug withdrawal. In this study, we used conditioned place aversion (...

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Publicado no:J Neurosci
Main Authors: Wang, Wei-Sheng, Kang, Shuo, Liu, Wen-Tao, Li, Mu, Liu, Yao, Yu, Chuan, Chen, Jie, Chi, Zhi-Qiang, He, Ling, Liu, Jing-Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704794/
https://ncbi.nlm.nih.gov/pubmed/23035088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1991-12.2012
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