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Sustainable Asymmetric Organolithium Chemistry: Enantio‐ and Chemoselective Acylations through Recycling of Solvent, Sparteine, and Weinreb “Amine”

The well‐established Hoppe–Beak chemistry, which involves enantioselective generation of organolithium compounds in the presence of (−)‐sparteine, was revisited and applied to unprecedented acylations with Weinreb amides to access highly enantioenriched α‐oxyketones and cyclic α‐aminoketones. Recycl...

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Detalhes bibliográficos
Publicado no:ChemSusChem
Main Authors: Monticelli, Serena, Holzer, Wolfgang, Langer, Thierry, Roller, Alexander, Olofsson, Berit, Pace, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704367/
https://ncbi.nlm.nih.gov/pubmed/30614208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cssc.201802815
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