Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss via Suppressing Osteoclastogenesis in Mice

Activation of osteoclast formation and function is crucial for the development of osteolytic diseases such as osteoporosis. RANKL (receptor activator of nuclear factor-κB ligand) activates NF-κB (nuclear factor κB), MAPK (mitogen-activated protein kinase), and NFATc1 (nuclear factor of activated T-c...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Huang, Bao, Wang, Jiasheng, Zhang, Xuyang, Xie, Ziang, Wu, Hao, Liu, Junhui, Jie, Zhiwei, Zhao, Xiangde, Qin, An, Fan, Shunwu, Chen, Jian, Zhao, Fengdong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704231/
https://ncbi.nlm.nih.gov/pubmed/31474861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00900
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