Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity

Tuberculous meningitis (TBM) is the most severe form of TB with high rates of mortality and morbidity. Here we conduct RNA-sequencing on whole blood as well as on ventricular and lumbar cerebrospinal fluid (CSF) of pediatric patients treated for TBM. Differential transcript expression of TBM cases a...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Rohlwink, Ursula K., Figaji, Anthony, Wilkinson, Katalin A., Horswell, Stuart, Sesay, Abdul K., Deffur, Armin, Enslin, Nico, Solomons, Regan, Van Toorn, Ronald, Eley, Brian, Levin, Michael, Wilkinson, Robert J., Lai, Rachel P. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704154/
https://ncbi.nlm.nih.gov/pubmed/31434901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11783-9
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