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Numerical operations in living cells by programmable RNA devices

Integrated bioengineering systems can make executable decisions according to the cell state. To sense the state, multiple biomarkers are detected and processed via logic gates with synthetic biological devices. However, numerical operations have not been achieved. Here, we show a design principle fo...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Endo, Kei, Hayashi, Karin, Saito, Hirohide
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703868/
https://ncbi.nlm.nih.gov/pubmed/31457099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax0835
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