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Crosslinked Chitosan-PEG Hydrogel for Culture of Human Glioblastoma Cell Spheroids and Drug Screening

Two-dimensional monolayer cell cultures are routinely utilized for preclinical cancer drug screening, but the results often do not translate well when drugs are tested in vivo. To address this limitation, a biocompatible chitosan-PEG hydrogel (CSPG gel) was synthesized to create a gel that can be ea...

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Detalhes bibliográficos
Publicado no:Adv Ther (Weinh)
Main Authors: Chang, Fei-Chien, Levengood, Sheeny Lan, Cho, Nick, Chen, Likai, Wang, Everet, Yu, John S., Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703847/
https://ncbi.nlm.nih.gov/pubmed/31435500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.201800058
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