Aromatase Inhibition Abolishes LTP Generation in Female But Not in Male Mice

Inhibitors of aromatase, the final enzyme of estradiol synthesis, are suspected of inducing memory deficits in women. In previous experiments, we found hippocampal spine synapse loss in female mice that had been treated with letrozole, a potent aromatase inhibitor. In this study, we therefore focuse...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Vierk, Ricardo, Glassmeier, Günter, Zhou, Lepu, Brandt, Nicola, Fester, Lars, Dudzinski, Danuta, Wilkars, Wiebke, Bender, Roland A., Lewerenz, Martha, Gloger, Simon, Graser, Lucas, Schwarz, Jürgen, Rune, Gabriele M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703647/
https://ncbi.nlm.nih.gov/pubmed/22699893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5319-11.2012
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