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Altered Distribution of Juxtaparanodal K(v)1.2 Subunits Mediates Peripheral Nerve Hyperexcitability in Type 2 Diabetes Mellitus

Peripheral nerve hyperexcitability (PNH) is one of the distal peripheral neuropathy phenotypes often present in patients affected by type 2 diabetes mellitus (T2DM). Through in vivo and ex vivo electrophysiological recordings in db/db mice, a model of T2DM, we observed that, in addition to reduced n...

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Vydáno v:J Neurosci
Hlavní autoři: Zenker, Jennifer, Poirot, Olivier, de Preux Charles, Anne-Sophie, Arnaud, Estelle, Médard, Jean-Jacques, Lacroix, Catherine, Kuntzer, Thierry, Chrast, Roman
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703576/
https://ncbi.nlm.nih.gov/pubmed/22649228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0719-12.2012
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