Neutralizing Activity of Anti-interferon-γ Autoantibodies in Adult-Onset Immunodeficiency Is Associated With Their Binding Domains

Adult-onset immunodeficiency (AOID) with anti-interferon-γ (IFN-γ) autoantibodies (autoAbs) is an emerging immunodeficiency syndrome in Asian countries. The presence of neutralizing anti-IFN-γ autoAbs are significantly associated with severe disseminated opportunistic infections. However, the charac...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yasamut, Umpa, Thongkum, Weeraya, Moonmuang, Sutpirat, Sakkhachornphop, Supachai, Chaiwarith, Romanee, Praparattanapan, Jutarat, Wipasa, Jiraprapa, Chawansuntati, Kriangkrai, Supparatpinyo, Khuanchai, Lai, Ethan, Tayapiwatana, Chatchai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702949/
https://ncbi.nlm.nih.gov/pubmed/31474987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01905
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