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Using the promoters of MerR family proteins as “rheostats” to engineer whole-cell heavy metal biosensors with adjustable sensitivity

BACKGROUND: Whole cell biosensors provide a simple method for the detection of heavy metals. However, previous designs of them rely primarily on simulation of heavy metal resistance systems of bacteria. RESULTS: This study proposes a strategy for the rational design of metal detection circuits based...

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Detalles Bibliográficos
Publicado en:J Biol Eng
Main Authors: Guo, Mingzhang, Du, Ruoxi, Xie, Zixin, He, Xiaoyun, Huang, Kunlun, Luo, Yunbo, Xu, Wentao
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702742/
https://ncbi.nlm.nih.gov/pubmed/31452678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0202-3
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