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Unraveling the molecular principles by which ceramides commit cells to death

Ceramides are central intermediates of sphingolipid metabolism that can activate a variety of tumor suppressive cellular programs, including cell cycle arrest, senescence and apoptosis. Indeed, perturbations in ceramide generation and turnover are frequently linked to cancer cell survival and resist...

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Detalhes bibliográficos
Publicado no:Cell Stress
Main Authors: Dadsena, Shashank, Hassan, Dina G., Holthuis, Joost C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702447/
https://ncbi.nlm.nih.gov/pubmed/31440742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2019.08.196
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