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A New View of the T-Loop Junction: Implications for Self-Primed Telomere Extension, Expansion of Disease-Related Nucleotide Repeat Blocks, and Telomere Evolution

Telomere loops (t-loops) are formed at the ends of chromosomes in species ranging from humans to worms, plants, and with genetic manipulation, some yeast. Recent in vitro studies demonstrated that transcription of telomeric DNA leads to highly efficient t-loop formation. It was also shown that both...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Tomaska, Lubomir, Nosek, Jozef, Kar, Anirban, Willcox, Smaranda, Griffith, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702307/
https://ncbi.nlm.nih.gov/pubmed/31475042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00792
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