Prediction of Treatment Response to Neoadjuvant Chemotherapy for Breast Cancer via Early Changes in Tumor Heterogeneity Captured by DCE-MRI Registration

We analyzed DCE-MR images from 132 women with locally advanced breast cancer from the I-SPY1 trial to evaluate changes of intra-tumor heterogeneity for augmenting early prediction of pathologic complete response (pCR) and recurrence-free survival (RFS) after neoadjuvant chemotherapy (NAC). Utilizing...

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Опубликовано в: :Sci Rep
Главные авторы: Jahani, Nariman, Cohen, Eric, Hsieh, Meng-Kang, Weinstein, Susan P., Pantalone, Lauren, Hylton, Nola, Newitt, David, Davatzikos, Christos, Kontos, Despina
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702160/
https://ncbi.nlm.nih.gov/pubmed/31431633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48465-x
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