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PI31 is an adaptor protein for proteasome transport in axons and required for synaptic development

Protein degradation by the ubiquitin-proteasome system is critical for neuronal function. Neurons utilize microtubule-dependent molecular motors to allocate proteasomes to synapses, but how proteasomes are coupled to motors and how this is regulated to meet changing demand for protein breakdown rema...

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Foilsithe in:Dev Cell
Main Authors: Liu, Kai, Jones, Sandra, Minis, Adi, Rodriguez, Jose, Molina, Henrik, Steller, Hermann
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702053/
https://ncbi.nlm.nih.gov/pubmed/31327739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.06.009
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