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Clinical Safety and Efficacy of Secondary Prophylactic Pegylated G-CSF in Advanced Pancreatic Cancer Patients Treated with mFOLFIRINOX: A Single-center Retrospective Study

OBJECTIVE: Although modified FOLFIRINOX (mFOLFIRINOX, mFFX) is widely used for patients with advanced pancreatic ductal adenocarcinoma (PDAC), maintenance of the standard dose intensity is often difficult due to the high incidence of neutropenic events. Pegylated granulocyte colony-stimulating facto...

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Bibliographic Details
Published in:Intern Med
Main Authors: Yamao, Kentaro, Takenaka, Mamoru, Yoshikawa, Tomoe, Ishikawa, Rei, Okamoto, Ayana, Yamazaki, Tomohiro, Nakai, Atsushi, Omoto, Shunsuke, Kamata, Ken, Minaga, Kosuke, Hagiwara, Satoru, Sakurai, Toshiharu, Nishida, Naoshi, Chiba, Yasutaka, Watanabe, Tomohiro, Kudo, Masatoshi
Format: Artigo
Language:Inglês
Published: The Japanese Society of Internal Medicine 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702006/
https://ncbi.nlm.nih.gov/pubmed/30996164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.2234-18
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