Lataa...

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary Ca(V)β subunits

Inhibiting high-voltage-activated calcium channels (HVACCs; Ca(V)1/Ca(V)2) is therapeutic for myriad cardiovascular and neurological diseases. For particular applications, genetically-encoded HVACC blockers may enable channel inhibition with greater tissue-specificity and versatility than is achieva...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Morgenstern, Travis J, Park, Jinseo, Fan, Qing R, Colecraft, Henry M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701945/
https://ncbi.nlm.nih.gov/pubmed/31403402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49253
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!