Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence

A mucosal infectious disease episode can render the host either more or less susceptible to recurrent infection, but the specific mechanisms that tip the balance remain unclear. We investigated this question in a mouse model of recurrent urinary tract infection and found that a prior bladder infecti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Yu, Lu, O'Brien, Valerie P, Livny, Jonathan, Dorsey, Denise, Bandyopadhyay, Nirmalya, Colonna, Marco, Caparon, Michael G, Roberson, Elisha DO, Hultgren, Scott J, Hannan, Thomas J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701943/
https://ncbi.nlm.nih.gov/pubmed/31429405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46677
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