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Dihydroxyacetone exposure alters NAD(P)H, induces mitochondrial stress and autophagy in HEK293T cells
Dihydroxyacetone phosphate (DHAP) is the endogenous by-product of fructose metabolism. Excess DHAP in cells can induce advanced glycation end products and oxidative stress. Dihydroxyacetone (DHA) is the triose precursor to DHAP. DHA is used as the active ingredient in sunless tanning products, inclu...
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| Publicado no: | Chem Res Toxicol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6701868/ https://ncbi.nlm.nih.gov/pubmed/31328504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00230 |
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