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Multilevel regression modeling for aneuploidy classification and physical separation of maternal cell contamination facilitates the QF-PCR based analysis of common fetal aneuploidies

BACKGROUND: The quantitative fluorescent polymerase chain reaction (QF-PCR) has proven to be a reliable method for detection of common fetal chromosomal aneuploidies. However, there are some technical shortcomings, such as uncertainty of aneuploidy determination when the short tandem repeats (STR) h...

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Publicado en:PLoS One
Main Authors: Noveski, Predrag, Terzic, Marija, Vujovic, Marija, Kuzmanovska, Maja, Sukarova Stefanovska, Emilija, Plaseska-Karanfilska, Dijana
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701765/
https://ncbi.nlm.nih.gov/pubmed/31430300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221227
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