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Novel methodology to image stromal tissue and assess its morphological features with polarized light: towards a tumour microenvironment prognostic signature

The amount and organization details of peri-tumoural stroma have been linked to patient outcomes in various cancers. In this study, we propose a novel and relatively simple methodology using polarized light microscopy (PLM) to image fibrillar structures within a tumour microenvironment, using only l...

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Detalhes bibliográficos
Publicado no:Biomed Opt Express
Main Authors: Westreich, Jared, Khorasani, Mohammadali, Jones, Blake, Demidov, Valentin, Nofech-Mozes, Sharon, Vitkin, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701544/
https://ncbi.nlm.nih.gov/pubmed/31452988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.10.003963
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