Identification and investigation of the vibrational properties of crystalline and co-amorphous drugs with Raman and terahertz spectroscopy

Co-amorphous drugs have shown significant potential in improving the stability and bioavailability compared with single neat amorphous drugs. Here, we explored the molecular interactions of cimetidine, naproxen, indomethacin and their binary co-amorphous mixtures via Raman and terahertz (THz) spectr...

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Udgivet i:Biomed Opt Express
Main Authors: Liu, Wei, Liu, Yu, Huang, Jiaoqi, Lin, Zhongquan, Pan, Xuancheng, Zeng, Xiaojun, Lamy de la Chapelle, Marc, Zhang, Yang, Fu, Weiling
Format: Artigo
Sprog:Inglês
Udgivet: Optical Society of America 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701517/
https://ncbi.nlm.nih.gov/pubmed/31453011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.10.004290
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