Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer’s disease

In this pilot study, we analyzed effects of transcranial photobiomodulation (tPBM, 1267 nm, 32 J/cm(2)) on clearance of beta-amyloid (Aβ) from the mouse brain. The immunohistochemical and confocal data clearly demonstrate the significant reduction of deposition of Aβ plaques in mice after tPBM vs. u...

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Bibliografiske detaljer
Udgivet i:Biomed Opt Express
Main Authors: Zinchenko, Ekaterina, Navolokin, Nikita, Shirokov, Alexander, Khlebtsov, Boris, Dubrovsky, Alexander, Saranceva, Elena, Abdurashitov, Arkady, Khorovodov, Alexander, Terskov, Andrey, Mamedova, Aysel, Klimova, Maria, Agranovich, Ilana, Martinov, Dmitry, Tuchin, Valery, Semyachkina-Glushkovskaya, Oxana, Kurts, Jurgen
Format: Artigo
Sprog:Inglês
Udgivet: Optical Society of America 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701516/
https://ncbi.nlm.nih.gov/pubmed/31452991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.10.004003
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