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Ultrasound-stimulated phase-change contrast agents for transepithelial delivery of macromolecules, towards gastrointestinal drug delivery
The gastrointestinal (GI) tract presents a notoriously difficult barrier for macromolecular drug delivery, especially for biologics. Herein, we demonstrate that ultrasound-stimulated phase change contrast agents (PCCAs) can transiently disrupt Caco-2 monolayers and improve the transepithelial transp...
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| Vydáno v: | Ultrasound Med Biol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6701470/ https://ncbi.nlm.nih.gov/pubmed/31003709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2019.02.004 |
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