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Next generation chimeric antigen receptor T cells: safety strategies to overcome toxicity

Chimeric antigen receptor T (CAR-T) cell therapy is an emerging and effective cancer immunotherapy. Especially in hematological malignancies, CAR-T cells have achieved exciting results. Two Anti-CD19 CAR-T therapies have been approved for the treatment of CD19-positive leukemia or lymphoma. However,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Yu, Shengnan, Yi, Ming, Qin, Shuang, Wu, Kongming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701025/
https://ncbi.nlm.nih.gov/pubmed/31429760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1057-4
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