Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism

BACKGROUND: Excessive estrogen exposure is an important pathogenic factor in uterine endometrial cancer (UEC). Recent studies have reported the metabolic properties can influence the progression of UEC. However, the underlying mechanisms have not been fully elucidated. METHODS: Glutaminase (GLS), MY...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Zhou, Wen-Jie, Zhang, Jie, Yang, Hui-Li, Wu, Ke, Xie, Feng, Wu, Jiang-Nan, Wang, Yan, Yao, Li, Zhuang, Yan, Xiang, Jiang-Dong, Zhang, Ai-Jun, He, Yin-Yan, Li, Ming-Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700828/
https://ncbi.nlm.nih.gov/pubmed/31429768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0412-9
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