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Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

BACKGROUND: African Americans (AAs) experience premature chronic health outcomes and longevity disparities consistent with an accelerated aging phenotype. DNA methylation (DNAm) levels at specific CpG positions are hallmarks of aging evidenced by the presence of age-associated differentially methyla...

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Pubblicato in:Clin Epigenetics
Autori principali: Tajuddin, Salman M., Hernandez, Dena G., Chen, Brian H., Noren Hooten, Nicole, Mode, Nicolle A., Nalls, Mike A., Singleton, Andrew B., Ejiogu, Ngozi, Chitrala, Kumaraswamy Naidu, Zonderman, Alan B., Evans, Michele K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700815/
https://ncbi.nlm.nih.gov/pubmed/31426852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0722-1
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