Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213

BACKGROUND: Androgen receptor (AR) plays important role in the development, progression, and metastasis of prostate cancer (PCa). Caffeic acid phenethyl ester (CAPE) is the main component of honey bee propolis. We determined if CAPE affects the signaling and stability of AR in PCa cells. METHODS: Ef...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Kuo, Ying-Yu, Huo, Chieh, Lin, Ching-Yu, Lin, Hui-Ping, Liu, Jai-Shin, Wang, Wen-Ching, Chang, Chuang-Rung, Chuu, Chih-Pin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700801/
https://ncbi.nlm.nih.gov/pubmed/31429764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0404-9
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