Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213

BACKGROUND: Androgen receptor (AR) plays important role in the development, progression, and metastasis of prostate cancer (PCa). Caffeic acid phenethyl ester (CAPE) is the main component of honey bee propolis. We determined if CAPE affects the signaling and stability of AR in PCa cells. METHODS: Ef...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Commun Signal
Prif Awduron: Kuo, Ying-Yu, Huo, Chieh, Lin, Ching-Yu, Lin, Hui-Ping, Liu, Jai-Shin, Wang, Wen-Ching, Chang, Chuang-Rung, Chuu, Chih-Pin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700801/
https://ncbi.nlm.nih.gov/pubmed/31429764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0404-9
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