Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer

BACKGROUND: miR-182-5p (miR-182) is an oncogenic microRNA (miRNA) found in different tumor types and one of the most up-regulated miRNA in colorectal cancer (CRC). Although this microRNA is expressed in the early steps of tumor development, its role in driving tumorigenesis is unclear. METHODS: The...

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Gepubliceerd in:BMC Cancer
Hoofdauteurs: Perilli, Lisa, Tessarollo, Sofia, Albertoni, Laura, Curtarello, Matteo, Pastò, Anna, Brunetti, Efrem, Fassan, Matteo, Rugge, Massimo, Indraccolo, Stefano, Amadori, Alberto, Bortoluzzi, Stefania, Zanovello, Paola
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700772/
https://ncbi.nlm.nih.gov/pubmed/31429725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5982-9
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