Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells

Cancer cells generally harbor hundreds of alterations in the cancer genomes and act as crucial factors in the development and progression of cancer. Gene alterations in the cancer genome form genetic interactions, which affect the response of patients to drugs. We developed an algorithm that mines c...

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Bibliografski detalji
Izdano u:Mol Ther Nucleic Acids
Glavni autori: Han, Yue, Wang, Chengyu, Dong, Qi, Chen, Tingting, Yang, Fan, Liu, Yaoyao, Chen, Bo, Zhao, Zhangxiang, Qi, Lishuang, Zhao, Wenyuan, Liang, Haihai, Guo, Zheng, Gu, Yunyan
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700431/
https://ncbi.nlm.nih.gov/pubmed/31400611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.07.003
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