Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells

Cancer cells generally harbor hundreds of alterations in the cancer genomes and act as crucial factors in the development and progression of cancer. Gene alterations in the cancer genome form genetic interactions, which affect the response of patients to drugs. We developed an algorithm that mines c...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Han, Yue, Wang, Chengyu, Dong, Qi, Chen, Tingting, Yang, Fan, Liu, Yaoyao, Chen, Bo, Zhao, Zhangxiang, Qi, Lishuang, Zhao, Wenyuan, Liang, Haihai, Guo, Zheng, Gu, Yunyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700431/
https://ncbi.nlm.nih.gov/pubmed/31400611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.07.003
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