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DNA Supercoiling: an Ancestral Regulator of Gene Expression in Pathogenic Bacteria?

DNA supercoiling acts as a global and ancestral regulator of bacterial gene expression. In this review, we advocate that it plays a pivotal role in host-pathogen interactions by transducing environmental signals to the bacterial chromosome and coordinating its transcriptional response. We present av...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Martis B., Shiny, Forquet, Raphaël, Reverchon, Sylvie, Nasser, William, Meyer, Sam
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700405/
https://ncbi.nlm.nih.gov/pubmed/31452857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.07.013
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