IP(3) receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP(3) receptors (IP3R) and the mitochondrial calcium uniporter, and are central to cell survival. It remains unclear whether IP3Rs also have a structural role in contact formation and whether the...

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Publicado no:Nat Commun
Main Authors: Bartok, Adam, Weaver, David, Golenár, Tünde, Nichtova, Zuzana, Katona, Máté, Bánsághi, Száva, Alzayady, Kamil J., Thomas, V. Kaye, Ando, Hideaki, Mikoshiba, Katsuhiko, Joseph, Suresh K., Yule, David I., Csordás, György, Hajnóczky, György
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700175/
https://ncbi.nlm.nih.gov/pubmed/31427578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11646-3
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