AAV-ie enables safe and efficient gene transfer to inner ear cells

Hearing loss is the most common sensory disorder. While gene therapy has emerged as a promising treatment of inherited diseases like hearing loss, it is dependent on the identification of gene delivery vectors. Adeno-associated virus (AAV) vector-mediated gene therapy has been approved in the US for...

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Vydáno v:Nat Commun
Hlavní autoři: Tan, Fangzhi, Chu, Cenfeng, Qi, Jieyu, Li, Wenyan, You, Dan, Li, Ke, Chen, Xin, Zhao, Weidong, Cheng, Cheng, Liu, Xiaoyi, Qiao, Yunbo, Su, Bing, He, Shuijin, Zhong, Chao, Li, Huawei, Chai, Renjie, Zhong, Guisheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700137/
https://ncbi.nlm.nih.gov/pubmed/31427575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11687-8
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