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The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells

We and others have previously shown that the canonical nuclear factor kappa-B (NF-κB) pathway is essential to nasopharyngeal carcinoma (NPC) tumor development and angiogenesis, suggesting that the NF-κB pathway, including its upstream modulators and downstream effectors, are potential therapeutic ta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lung, Hong Lok, Kan, Rebecca, Chau, Wai Yin, Man, On Ying, Mak, Nai Ki, Fong, Chun Hung, Shuen, Wai Ho, Tsao, Sai Wah, Lung, Maria Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700134/
https://ncbi.nlm.nih.gov/pubmed/31427673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48590-7
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